<i>Lactobacillus salivarius</i> UCC118™ Dampens Inflammation and Promotes Microbiota Recovery to Provide Therapeutic Benefit in a DSS-Induced Colitis Model.

In the DSS treatment groups, PBS mice had a slight trend towards increased tissue damage compared to UCC118TM mice; however, cell infiltration scores were similar across both groups ( Supplementary Figure S1 ).

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Mice pretreated with UCC118TM were effectively protected from DSS-induced weight loss ( Figure 1 A) and showed a trend towards reduced rectal bleeding ( Figure 1 B) and diarrhoea ( Figure 1 C) in the early stages of DSS treatment.

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UCC118TM treatment resulted in lower IL-6 levels in the colon compared to DSS + PBS mice, though the trend did not reach statistical significance ( Figure 7 C).

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