Direct oral anticoagulants versus low-molecular-weight heparins for the treatment of acute venous thromboembolism in patients with gastrointestinal cancer: a systematic review and meta-analysis.

Thromb J · 2022 · PMC9330678 · PMID 35902879

Europe PMC DOI

hedged sentences

0.2300

closest p · 4.6× alpha

0.2900

boldest claim

The sentences

did not reach statistical significanceP = 0.23not close (p > 0.1)

However, the pooled effect estimate did not reach statistical significance (95% CI: 0.84–2.04; P = 0.23).

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showed a trendP = 0.29not close (p > 0.1)

However, the patients who received DOACs showed a trend toward more major bleeding, with a pooled RR of 1.83 (95% CI: 0.60–5.56; P = 0.29; I2 = 0%; Fig. 6 B) [ 11 , 22 , 24 ].

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