The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

Although siRNA #8 showed no significant mean delay, individual cells still showed a trend towards delayed anaphase onset.

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Although we did detect a slight increase in multinucleated cells and multilobed nuclei in HECTD1-depleted cells, this did not reach statistical significance (Supplementary Fig. 5 D–F).

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