Iron accumulation typifies renal cell carcinoma tumorigenesis but abates with pathological progression, sarcomatoid dedifferentiation, and metastasis.

Front Oncol · 2022 · PMC9389085 · PMID 35992801

Europe PMC DOI

hedged sentences

0.0580

closest p · 1.2× alpha

0.0580

boldest claim

The sentences

approached significancep = 0.058so close (0.05 < p ≤ 0.1)

An association between lower RCC TME iron and metastatic stage approached significance (p = 0.058) ( Table 4 ).

also in 8,237 other papers

did not reach statistical significanceno p-value reported

Lower RCC cell iron was significantly associated with worse pathological stage and grade ( Figures 3B , C ), whereas similar associations with larger tumor size (p = 0.12) and sarcomatoid dedifferentiation (p = 0.097) did not reach statistical significance ( Figures 3A , D ).

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.