Barely Significant
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Correlations between APOE4 allele and regional amyloid and tau burdens in cognitively normal older individuals.

Sci Rep · 2022 · PMC9395408 · PMID 35995824

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showed a trendno p-value reported
Cortical thickness did not show any group differences, although group 2 showed a trend of greater cortical thinning in parts of the frontal, parietal, and temporal cortical areas compared with group 0 (Supplementary Fig. 2 C).

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Our results also showed similar trends to the previous AD studies that high tau depositions in medial temporal region in APOE4 + AD participants, although it did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.