Pharmacogenomics of Monoclonal Antibodies for the Treatment of Rheumatoid Arthritis.

J Pers Med · 2022 · PMC9410311 · PMID 36013214

Europe PMC DOI

hedged sentences

0.0400

closest p · 0.8× alpha

0.0400

boldest claim

The sentences

nominally significantp = 0.04actually significant

The RGS12 SNP rs4690093 confirmed a nominally significant association between the clinical response to ADA (OR = 0.4; CI 95% = 0.17–0.98; p = 0.04).

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a significant trendno p-value reported

RA patients with the low-affinity FCGR2A -RR genotype had a significantly better ACR20 response (RR: 60% and HH-RH: 33.3%; p = 0.035), while EULAR good and moderate responses only showed a significant trend after 30 weeks of IFX treatment (RR: 38.1% and HH-RH: 25.0%).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.