Identification of risk loci for primary aldosteronism in genome-wide association studies.

Differences in CASZ1 mRNA expression were also observed by RT-qPCR on a smaller set of samples, although this did not reach statistical significance (Supplementary Fig. 4 c).

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In addition, carriers of the risk allele at rs1869799 and rs1535532 also showed a trend towards higher cortisol over aldosterone ratio (Supplementary Fig. 9 b, d), and carriers of the risk allele at rs1902272 a trend towards lower corticosterone levels (Supplementary Fig. 9 f).

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