Erythrocyte complement receptor 1 (ECR1) and erythrocyte-bound C4d (EC4d) in the prediction of poor pregnancy outcomes in systemic lupus erythematosus (SLE).

Lupus Sci Med · 2022 · PMC9445792 · PMID 36755365

Europe PMC DOI

hedged sentences

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closest p · 1.2× alpha

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boldest claim

The sentences

approached significancep=0.06so close (0.05 < p ≤ 0.1)

When baseline visits in the first and second trimesters (n=53) were analysed, ECR1 <5.5 net MFI, as determined by maximised Youden’s Index, was statistically significant at predicting APO (t-test p=0.05) and approached significance for preterm delivery (t-test p=0.06) with DOR of 12.33 (95% CI: 2.41 to 63.10) and 12.19 (95% CI: 2.30 to 64.72), respectively ( table 3 ).

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did not reach statistical significanceno p-value reported

Other individual biomarkers did not reach statistical significance.

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