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TROP2 Represents a Negative Prognostic Factor in Colorectal Adenocarcinoma and Its Expression Is Associated with Features of Epithelial-Mesenchymal Transition and Invasiveness.

Cancers (Basel) · 2022 · PMC9454662 · PMID 36077674

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Although a trend toward the formation of smaller xenograft tumors was observed in vivo, this difference did not reach statistical significance.

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A multivariate Cox regression identified high TROP2 expression together with lymph node metastases and an age older than 75 years as an independent negative prognostic factor for poor CSS, whereas CK7 reached borderline significance ( Figure 2 D). 3.3.

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