Sperm DNA methylation alterations from cannabis extract exposure are evident in offspring.

Epigenetics Chromatin · 2022 · PMC9463823 · PMID 36085240

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

approached significancep = 0.06so close (0.05 < p ≤ 0.1)

4 A), and the difference approached significance when comparing the F1 sperm from EE and control offspring ( p = 0.06).

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nominally significantno p-value reported

There were 3321 nominally significant differentially methylated CpGs in F0 sperm identified via WGBS with select methylation changes validated via bisulfite pyrosequencing.

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