Identification of a 5-gene-based signature to predict prognosis and correlate immunomodulators for rectal cancer.

Associations between the risk-score and other clinicopathological features, such as stage and lymphatic invasion, failed to reach statistical significance in the TCGA dataset ( Table 1 ).

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Myeloid dendritic cells were found to be almost significantly different between the two groups ( Fig. 7 C-D).

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The TCGA rectal cancer dataset was stratified into high versus low hsa-miR-6887-expressing groups, and then, upon Kaplan–Meier survival analysis, high hsa-miR-6887-expressing tumors showed a tendency toward an improved outcome for patients, but this did not reach statistical significance ( Fig. 8 B).

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