Kanamycin and Cisplatin Ototoxicity: Differences in Patterns of Oxidative Stress, Antioxidant Enzyme Expression and Hair Cell Loss in the Cochlea.

Cisplatin ABR recordings performed within 24 h after administration of cisplatin in single injection showed a trend towards elevated thresholds, particularly above 4 KHz.

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Such threshold shifts, however, did not reach statistical significance at any tested frequency ( Figure 2 ).

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