Furthermore, the amino acids aspartate, serine, and glycine, which function as important precursors for TCA cycle anaplerosis and nucleotide biosynthesis ( Figure 6—figure supplement 1C ), were also significantly induced by Chlamydia infection, while glutamine showed a trend towards induction that failed to reach statistical significance.
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c-Myc plays a key role in IFN-γ-induced persistence of <i>Chlamydia trachomatis</i>.
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