Genome-wide association analyses of common infections in a large practice-based biobank.

BMC Genomics · 2022 · PMC9512962 · PMID 36167494

Europe PMC DOI

hedged sentences

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closest p · 0.0× alpha

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boldest claim

The sentences

close-to-significantp = 2.59 × 10 –6actually significant

, did not replicate, there was a close-to-significant association between HLA-DQB1 and the risk of infectious mononucleosis ( p = 2.59 × 10 –6 , Supplementary Table 4 ).

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nominally significantp < 10 –5actually significant

Additionally, several of these four disease-transcriptome associations were nominally significant ( p < 10 –5 ) in several other tissues (Supplementary Table 4 ).

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