Exosomal telomerase transcripts reprogram the microRNA transcriptome profile of fibroblasts and partially contribute to CAF formation.

Sci Rep · 2022 · PMC9525320 · PMID 36180493

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did not reach statistical significanceno p-value reported

In each time point the effect was telomerase mediated to some degree since it was milder in treated fibroblasts with telomerase inhibition compared to exosomal exposed cells, although did not reach statistical significance in all cases (Fig. 5 ).

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a clear trendno p-value reported

In our setting, we found a clear trend of increase in IL-6 secretion levels from the exosomally exposed fibroblasts.

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