Vibrio cholerae high cell density quorum sensing activates the host intestinal innate immune response.

All showed a trend toward decreased expression in Δ hapR mutant infection ( Figure 6D ).

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cholerae or a Δ hapR mutant, transcription of aceB , the gene encoding malate synthase, was significantly increased, whereas the increase in transcription of aceA , the gene encoding isocitrate lyase, did not reach statistical significance.

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