In a phase 2 placebo-controlled trial abatacept treatment also improved general health in patients with early dcSSc and showed a trend for skin improvement in the abatacept treated group [ 184 ].
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CD8<sup>+</sup> T Cell Phenotype and Function in Childhood and Adult-Onset Connective Tissue Disease.
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There was also a trend for an increase in DM, though this did not reach statistical significance [ 88 ]. 3.2.