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Evaluation of ketoconazole as a treatment for Cushing's disease in a retrospective cohort.

Front Endocrinol (Lausanne) · 2022 · PMC9585352 · PMID 36277689

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showed a trendno p-value reported
Our analyses showed a trend toward a response that continued, with some oscillations, over time.

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a clear trendno p-value reported
Since 75% of the CD patients who used ketoconazole had a complete or partial response, there was a clear trend towards improvement in hypercortisolism.

also in 19,460 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.