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Diverse maturity-dependent and complementary anti-apoptotic brakes safeguard human iPSC-derived neurons from cell death.

Cell Death Dis · 2022 · PMC9587001 · PMID 36270985

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Mature neurons also showed a tendency to cope better with MG132 (inhibitor of the ubiquitin-proteasome system) exposure but the observed differences did not reach statistical significance.

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showed a trendno p-value reported
More mature neurons showed a trend towards slightly more negative resting membrane potential (RMP), significantly decreased input resistance and significantly increased membrane capacitance (Supplementary Fig. 1B ).

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