Interestingly, GT3 showed a trend of increased ZO-1, claudin-7, and occludin levels at day 4, but the trend did not persist by day 7 (data not shown).
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Effects of Gamma-Tocotrienol on Partial-Body Irradiation-Induced Intestinal Injury in a Nonhuman Primate Model.
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The data show that TUNEL positivity (irreversible cell death) was overall very low, no more than 0.4% of the total cells, and GT3 provided some mitigation of the injury at day 4 compared to the vehicle, which did not reach statistical significance.