Tau antibody 77G7 targeting microtubule binding domain suppresses proteopathic tau to seed tau aggregation.

40 In the present study, intravenous administration of 77G7 decreased or showed a trend to decrease tau phosphorylation.

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AT8 immunoactivity was less but did not reach statistical significance in both ipsilateral and contralateral hippocampi of 77G7 iv‐injected mice (Figure 6B,C ).

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