Inflammation and immune activation are associated with risk of Mycobacterium tuberculosis infection in BCG-vaccinated infants.

Nat Commun · 2022 · PMC9632577 · PMID 36329009

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did not reach statistical significanceno p-value reported

The number of infants who became infected with M.tb was higher in the CMV-infected group, though this did not reach statistical significance.

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showed a trendno p-value reported

We have previously shown that although only Ag85A-specific IgG on Day 28 were associated with a significantly reduced risk of TB disease, Ag85A-specific IgG on Day −7 also showed a trend towards an association with reduced risk of TB disease that did not reach statistical significance 6 .

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