Candidate gene analysis revealed several nominally significant associations with plasma MI, most notably for SLC5A11 (solute carrier family 5 member 11), encoding a sodium-coupled inositol transporter, also known as SMIT2 (sodium-dependent myo -inositol transporter 2).
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Investigating Genetic Determinants of Plasma Inositol Status in Adult Humans.
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However, none of these SNPs showed significant association with MI, following adjustment of the threshold for significance to account for multiple tests (106 independent SNPs; Bonferroni-adjusted P value <0.0005 by study), although RS28540434 approached significance.