Clinical improvement of DM1 patients reflected by reversal of disease-induced gene expression in blood.

BMC Med · 2022 · PMC9646470 · PMID 36352383

Europe PMC DOI

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nominally significantno p-value reported

For 81 of the 97 candidate biomarkers, the Pearson correlations were nominally significant for the change in gene expression and the compound response score.

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a clear trendno p-value reported

Most interestingly, an overlap of 97 genes among these latter two gene sets has been identified, showing a clear trend of more normal expression levels in clinical responders.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.