Barely Significant
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Signaling underlying kappa opioid receptor-mediated behaviors in rodents.

Front Neurosci · 2022 · PMC9670127 · PMID 36408401

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showed a trendno p-value reported
(2019) reported that U50,488H (2.5 mg/kg) increased the ICSS threshold and showed a trend of decreasing maximal wheel-spinning rates but did not reach statistical significance.

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