Conclusion These findings indicate that apoC-III lowering will have a marked effect on TRL and remnant metabolism, with possibly significant consequences for cardiovascular disease prevention.
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Postprandial metabolism of apolipoproteins B48, B100, C-III, and E in humans with APOC3 loss-of-function mutations.
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The sentences
There was a nominally significant difference noted in direct LDL apoB100 synthesis ( Supplemental Table 3 ).
These differences were nominally significant ( P < 0.05) with the exception of the VLDL 1 apoB48 FCR and the TG-apoB48 VLDL 1 FCR, which showed a trend of approximately the same magnitude.