Dextrose Prolotherapy for Symptomatic Grade IV Knee Osteoarthritis: A Pilot Study of Early and Longer-Term Analgesia and Pain-Specific Cytokine Concentrations.

Clin Pract · 2022 · PMC9680458 · PMID 36412676

Europe PMC DOI

hedged sentences

0.0280

closest p · 0.6× alpha

0.0280

boldest claim

The sentences

near significancep = 0.028actually significant

approached significancep = 0.07so close (0.05 < p ≤ 0.1)

SP concentration increased by near significance by one week within the Dextrose-1st group ( p = 0.028), and the between-group difference also approached significance ( p = 0.07).

also in 505 other papers

near-significantno p-value reported

Although IGF-1 stimulates the proliferation of chondrocytes in vitro, with chondroinductive actions equally potent to TGF-β [ 41 ], its increase in the current study was accompanied by a near-significant increase in a catabolic cytokine (IL-6).

also in 2,306 other papers

approaching clinical significanceno p-value reported

The baseline NRS scores tended to be higher in the Aspiration-1st group, approaching clinical significance, and the baseline NRS score was included as a covariate for statistical analysis.

also in 21 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.