Current radiotherapy for recurrent head and neck cancer in the modern era: a state-of-the-art review.

Although the 2-year OS was 60% for patients with HPV+ recurrence or second primary oropharyngeal cancer compared with 39.5% for patients with HPV-negative cancer, this result did not reach statistical significance.

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Furthermore, age > 70 years old was associated with a poor OS, while previous salvage surgery showed a trend to improve LC and OS [ 29 ].

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This indicated a positive trend by the additional use of the cetuximab plus taxane regimen.

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