Impact of BRCA Mutation Status on Tumor Dissemination Pattern, Surgical Outcome and Patient Survival in Primary and Recurrent High-Grade Serous Ovarian Cancer: A Multicenter Retrospective Study by the Ovarian Cancer Therapy-Innovative Models Prolong Survival (OCTIPS) Consortium.

Ann Surg Oncol · 2023 · PMC9726811 · PMID 36085390

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failed to reach statistical significanceno p-value reported

Age (OR 0.972; CI 95% 0.939–1.007; p = 0.115) and surgical complexity (OR 0.557; CI 95% 0.207–1.501; p = 0.247) failed to reach statistical significance.

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did not reach statistical significanceno p-value reported

Although the difference in patients with pOC disease with complete tumor resection did not reach statistical significance compared with the BRCA wt group, optimal debulking was significantly more often achieved during rOC surgery in the BRCA mut cohort.

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