Peak Plasma Levels of mtDNA Serve as a Predictive Biomarker for COVID-19 in-Hospital Mortality.

Thereafter, the plasma levels of mtDNA in the patient group continued to increase compared with those of the control group (t 72 ), but did not reach statistical significance (controls: 65 (28–119) copies/μL; patients: 281 (110–805) at t 0 , 403 (168–1937) at t 24 and 467 (188–952) copies/μL at t 72 ; controls vs. patients: p = 0.02 at t 0 , p = 0.03 at t 24 and p = 0.44 at t 72 ; Figure 1 B).

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However, the data at the final time point of 72 h ( Figure 2 ) failed to reach statistical significance, most possibly owing to the small number of included cases.

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