2022 Annual World Congress of the Pulmonary Vascular Research Institute

Pulm Circ · 2022 · PMC9748629

Europe PMC

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did not reach statistical significanceno p-value reported

15%) but did not reach statistical significance.

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highly significantno p-value reported

Fourth, a PAH BioBank genome‐wide association study (GWAS; 674 iPAH subjects and 250 controls) identifies three NAMPT single‐nucleotide polymorphisms (SNPs; rs61330082, rs9770242 and rs59744560), previously linked to inflammatory injury severity, including acute respiratory distress syndrome mortality, to exhibit highly significant associations with indices of RV dysfunction and PAH severity, including cardiac output, peripheral vascular resistance (PVR) and RV stroke work index.

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showed a trendno p-value reported

The CTED patients showed a trend towards a higher peak O 2 consumption.

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