Multicomponent drug Neurexan mitigates acute stress-induced insomnia in rats.

J Sleep Res · 2022 · PMC9786571 · PMID 35060218

Europe PMC DOI

hedged sentences

0.0570

closest p · 1.1× alpha

0.0570

boldest claim

The sentences

a strong trendp = 0.057so close (0.05 < p ≤ 0.1)

In addition, there was also a strong trend ( p = 0.057) with Nx4 CEX rats spending 12.7 min more time in NREM sleep than Veh CEX.

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showed a trendno p-value reported

Clinical evidence also found that compared with placebo, Nx4 significantly reduced stress‐induced increases in stress biomarkers including, salivary cortisol and plasma adrenaline and showed a trend to diminish stress‐induced increase in plasma cortisol (Doering et al., 2016 ).

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