Neuroprotection by Preconditioning in Mice is Dependent on MyD88-Mediated CXCL10 Expression in Endothelial Cells.

CD105 (endoglin) and TLR4 ( Li et al., 1999 ) showed a trend toward increased expression 24 hr after the fourth LPS injection ( Figure 1D ), but mean fluorescence intensities (MFIs) did not reach statistical significance.

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Nevertheless, an apparent trend toward increased claudin-5 and occludin after one dose of LPS treatment may indicate enhanced protection of the BBB ( Figure 1C ).

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