Roles of oral microbiota and oral-gut microbial transmission in hypertension.

The difference in β-diversity of salivary microbiota also showed a statistical trend (p = 0.056) between the two groups ( Fig. 2 D).

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Moreover, in saliva and subgingival plaques, Bacteroidetes were enriched in no HTN, whereas Actinobacteria and Fusobacteria were enriched in HTN group; in feces, Bacteroidetes , Proteobacteria , Actinobacteria and Fusobacteria were enriched in HTN group, although these differences did not reach statistical significance ( Fig. 3 B).

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When non-hypertensive and hypertensive participants were analyzed separately, non-hypertensive participants with PD showed a strong trend to have higher SBP than no PD ( Fig. 1 B), and hypertensive participants with PD showed significantly higher SBP than no PD ( Fig. 1 C).

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