Methylation in MAD1L1 is associated with the severity of suicide attempt and phenotypes of depression.

Clin Epigenetics · 2023 · PMC9811786 · PMID 36600305

Europe PMC DOI

hedged sentences

0.0890

closest p · 1.8× alpha

0.0890

boldest claim

The sentences

showed a trendp value ~ 0.089so close (0.05 < p ≤ 0.1)

The same locus showed increased methylation in glial cells (exp( β ) = 0.041, p value ~ 0.004) in the validation cohort, involving 29 depressed patients and 29 controls, and showed a trend for association with suicide ( n = 40, p value ~ 0.089) and trend for association with depression treatment ( n = 377, p value ~ 0.075).

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nominally significantno p-value reported

Nominally significant associations (raw p value) were considered.

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