Effectiveness of Hyperbaric Oxygen Therapy in SARS-CoV-2 Pneumonia: The Primary Results of a Randomised Clinical Trial.

J Clin Med · 2022 · PMC9820955 · PMID 36614808

Europe PMC DOI

hedged sentences

0.0670

closest p · 1.3× alpha

0.0670

boldest claim

The sentences

did not reach statistical significancep = 0.067so close (0.05 < p ≤ 0.1)

The difference in death rate did not reach statistical significance (21.4% vs. 0.0%, p = 0.067).

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a clear trendno p-value reported

Conclusions This analysis of our prospective RCT on using HBOT in severe COVID-19 confirmed the effectiveness of randomisation (except for IL-6), showed a clear trend towards fewer deaths in the HBOT group, confirmed the possibility of safely conducting HBOT in this patient group, showed a lower need for normobaric oxygenation in the group of patients treated with HBOT and demonstrated significant beneficial effects of HBOT on CRP, ferritin, LDH and CD3.

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