Comprehensive narrative review on the analysis of outcomes from cell transplantation clinical trials for discogenic low back pain.

N Am Spine Soc J · 2023 · PMC9841054 · PMID 36655116

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showed a trendno p-value reported

[42] similarly showed clear differences between their control and cell-treated cohorts, resulting in a significant improvement of about 20-point ODI 3.5 years following cell therapy, while the control group showed a trend of about 10-point ODI worsening.

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a clear trendno p-value reported

Again, focusing on the cell treatment complementing microdiscectomy, a clear trend of improvement in outcomes can be observed.

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a slight trendno p-value reported

treating microdiscectomy patients with autologous IVD derived-cells, was similarly able to report alleviation in pain (a 42% reduction), which resulted only in a slight trend of enhanced pain outcomes compared to a discectomy-only cohort.

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