MR imaging profile and histopathological characteristics of tumour vasculature, cell density and proliferation rate define two distinct growth patterns of human brain metastases from lung cancer.

Neuroradiology · 2023 · PMC9859874 · PMID 36184635

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.0548

boldest claim

The sentences

showed a trendp = 0.05actually significant

We identified two distinct BM growth patterns depending on their proliferative status: Ki67 high BMs were larger ( p = 0.02), showed less peritumoural oedema ( p = 0.02) and showed a trend towards higher cell density ( p = 0.05).

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a strong trendp = 0.0548so close (0.05 < p ≤ 0.1)

Cell density assessed by DAPI nuclear staining showed a strong trend towards a higher cell density in Ki67 high BM ( p = 0.0548, Fig. 4 , Table 1 ).

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