Barely Significant
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Older patients with Hodgkin Lymphoma: Walking the tightrope of efficacy and toxicity.

Front Oncol · 2022 · PMC9880490 · PMID 36713561

Europe PMCDOI
2
hedged sentences
0.4430
closest p · 8.9× alpha
0.4430
boldest claim

The sentences

showed a trendp=0.443not close (p > 0.1)
A subgroup analysis of 186 ECHELON-1 patients >60y with a median age of 67y showed a trend towards improvement in 5-year PFS in the BV+AVD arm which was not significant (67.1% versus 61.6%, p=0.443).

also in 53,322 other papers

did not reach statistical significanceno p-value reported
The PFS differential did not reach statistical significance in the older cohort specifically but this was an underpowered subgroup analysis, indicating that further study in older patients is warranted.

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.