Acid sphingomyelinase promotes diabetic cardiomyopathy via NADPH oxidase 4 mediated apoptosis.

Cardiovasc Diabetol · 2023 · PMC9896821 · PMID 36732747

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showed a trendno p-value reported

1 g) just showed a trend of reduction.

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an increasing trendno p-value reported

1 i–l) showed an increasing trend.

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did not reach statistical significanceno p-value reported

Again, the immumohistochemical staining data mirrored that ceramide content tended to decrease in HFD ASMase-knockdown hearts, however, the decrease did not reach statistical significance and higher than control groups (Fig. 7 e), suggesting that ceramide is not too affected by ASMase knockdown.

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