Comparative Analysis of Normoxia- and Hypoxia-Modified Extracellular Vesicle Therapy in Function, Perfusion, and Collateralization in Chronically Ischemic Myocardium.

Int J Mol Sci · 2023 · PMC9916784 · PMID 36768399

Europe PMC DOI

hedged sentences

0.0550

closest p · 1.1× alpha

0.0550

boldest claim

The sentences

a strong trendp = 0.055so close (0.05 < p ≤ 0.1)

There were no significant differences in the expression of p-eNOS ( p = 0.41) or total eNOS ( p = 0.15), though there was a strong trend towards a decreased p-eNOS to eNOS ratio ( p = 0.055) in the HYP group compared to NOR.

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did not reach statistical significanceno p-value reported

Though there were trends towards improved perfusion at rest and during pacing with hypoxia-modified EV therapy compared to the normoxia EVs, these trends did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.