Barely Significant
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Immunohistochemical Expression Analysis of Caldesmon Isoforms in Colorectal Carcinoma Reveals Interesting Correlations with Tumor Characteristics.

Int J Mol Sci · 2023 · PMC9916900 · PMID 36768598

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However, few cases with high l-CaD expression received 5FU alone and showed a trend to have poor survival that did not reach statistical significance.

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showed a trendno p-value reported
In contrast, l-CaD expression showed a trend for association with poor survival after 5FU therapy alone, suggesting that it predisposes to resistance to 5FU.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.