The efficacy of thoracic radiotherapy in extensive stage small cell lung cancer with baseline brain metastases: a multi-institutional retrospective cohort study.

Ann Transl Med · 2023 · PMC9929839 · PMID 36819545

Europe PMC DOI

hedged sentences

0.0040

closest p · 0.1× alpha

0.0900

boldest claim

The sentences

failed to reach statistical significanceP = 0.004actually significant

Although the primary endpoint of 1-year OS rate failed to reach statistical significance, a post-hoc analysis revealed that the 2-year OS rate was significantly increased in the TRT group (13% vs. 3%, P = 0.004) ( 3 ).

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showed a trendP=0.09so close (0.05 < p ≤ 0.1)

reported that in patients with less than three distant metastases, TRT significantly improved the PFS (HR 2.02, P=0.003) and also showed a trend of improving OS (HR 1.55, P=0.09).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.