The Role of Green Tea Catechin Epigallocatechin Gallate (EGCG) and Mammalian Target of Rapamycin (mTOR) Inhibitor PP242 (Torkinib) in the Treatment of Spinal Cord Injury.

Antioxidants (Basel) · 2023 · PMC9952296 · PMID 36829922

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.9326

boldest claim

The sentences

a strong trendp = 0.05actually significant

Treatment with mTOR inhibitor PP242 also displayed a significantly improved BBB score over the course of 6, 7, and 8 weeks ( p = 0.042, p = 0.047, and p = 0.025), and there was a strong trend ( p = 0.05–0.1) from 1–5 weeks after SCI.

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a trend towards significancep = 0.098so close (0.05 < p ≤ 0.1)

A significantly shorter response time was also seen in PP242 in week three compared with controls ( p = 0.05), and a trend towards significance was also seen when compared with controls in week seven after SCI ( p = 0.098)(Two-way RM ANOVA, F = 0,7677, p = 0.6830). 3.2.

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failed to reach significancep = 0.9326not close (p > 0.1)

EGCG-, PP242-and-EGCG-, and PP242-treated rats showed higher scores when compared to the saline-treated controls, although they failed to reach significance (ANOVA F = 0.5120, p = 0.9326).

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did not reach statistical significanceno p-value reported

However, they did not reach statistical significance. 3.1.4.

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