More prominently, patients with high Mφ density (CD68 Hi ) showed a trend towards a longer median OS compared with patients with low Mφ density (CD68 Lo ), although this did not reach statistical significance (15.0 months vs. 10.4 months, P = 0.11; Fig. 1 B).
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Co-enrichment of CD8-positive T cells and macrophages is associated with clinical benefit of tislelizumab in solid tumors.
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