Barely Significant

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Although the National Institute of Neurological Disorders and Stroke (NINDS) rt-PA Stroke Study did not identify a significant difference in the beneficial effects of IV t-PA in patients with minor strokes compared to those who received a placebo, there was an observed trend suggesting that minor stroke patients who received IV t-PA experienced favorable outcomes [ 21 ].
However, in cases where children present with persistent microscopic haematuria often accompanied by episodes of visible blood in the urine (gross hematuria), there may be significant anxiety for both patients and their families, leading to a strong desire for a definitive diagnosis [ 28 ].
Alport Syndrome: A Comprehensive Review.
Cureus · 2023 · PMC10649250