Bodyweight A three-way ANOVA evaluating change in bodyweight from 4 months (time of irradiation) to 11 months (beginning of behavior tests) of age revealed an unexpected highly significant main effect of radiation exposure ( p = 0.01) and an expected significant effect of sex ( p = 0.04) ( Figure 1 C).
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In the hepatopancreas ( Figure 5 B), both Mn-HexA1 and Mn-HexA2 displayed a highly significant increase in expression from stage He1 (hepatopancreas in O1 stage) to He2 (hepatopancreas in O2 stage) ( p < 0.01), reaching peak levels at He2 stage that were substantially higher than all other developmental stages ( p < 0.01).
The results showed a highly significant correlation between sphingolipid metabolism and key metabolites in pyrimidine metabolism ( p < 0.01, Figure S3 ).
Statistical differences were interpreted as significant at p ≤ 0.05 *, highly significant at p ≤ 0.01 **, and extremely significant at p ≤ 0.001 *** or p ≤ 0.0001 ****. 5.
Among these DAMs, 30 metabolites showed extremely significant differences between control and NaCl treatment ( p < 0.01) ( Figure 8 A) and were involved in different metabolic pathways, including CBB and TCA cycles ( Figure 8 A).
Statistical differences were considered as significant if the p-values were below the significance threshold of 0.05 (* p ≤ 0.05) and were considered highly significant if the p -values were less than 0.01 (** p ≤ 0.01) or even less than 0.001 (*** p ≤ 0.001).
Postoperative anti-glaucoma medications showed a highly significant intergroup difference ( p = 0.01), being most frequent in RRD (56.9%), followed by dropped IOL/lens (50.0%).
The root node, deviations from Hardy–Weinberg equilibrium, spawns two branches: highly significant ( p < 0.01) and significant ( p < 0.05) values, and non-significant ( p > 0.05) and undetermined (ND) values.
The results were considered statistically significant with a p -value < 0.05 and highly significant with a p -value < 0.01.
Differences were considered significant at p < 0.05 (*) and as highly significant at p ≤ 0.01 (**) and p ≤ 0.001 (***).
The upregulation of KRT17 upregulated WNT2 and FGF2 but downregulated TGFβ1, SFRP2, and BMP2, all showing extremely significant differences ( p < 0.01) ( Figure 5 D,E).
A series of highly significant correlations (r s = 1.000, p < 0.01) were identified among Otx2 protein levels across multiple ocular tissues, including the lens, optic nerve, ciliary body, iris, sclera, and eyelid.
In Δ7SMA mice, miR-133a and miR-133b showed an opposite trend, since both the two miRNAs were up-regulated at symptomatic disease phase (day 10), although differences did not reach statistical significance for miR-133b (as illustrated in Figure 1 B; ** p < 0.01 for miR-133a).
A clear and highly significant ( p < 0.01) in-crease in the abundance of transcripts of all glycosylases (MPG, TDG, and OGG1) was observed in the PCx after administration of the lower KYNA dose compared to the control group.
As shown in Table 3 , the regression model was highly significant ( p < 0.01), and the out-of-fit term p = 0.1379 was not significant (confidence level of 95%), indicating a good fit of the model.
Differences were considered highly significant at p < 0.01 and significant at p < 0.05. 4.7.
At stages A and B, the number of GO terms enriched by DEGs in Molecular Function was 1111 and 1204, respectively, among which 113 and 107 terms showed highly significant differences ( p < 0.01).
In our study, DL-glutamic acid, DL-aspartic acid, DL-citrulline, and spermidine were highly significant across all pain subgroups (MS/NV/NP) compared to controls ( p < 0.01), while DL-ornithine showed significance in MS and NV subgroups ( p < 0.05).
Additionally, most of the grain minerals had highly significant positive correlations ( p < 0.01) among each other.
Differences were considered significant at p < 0.05 and extremely significant at p < 0.01.
Statistical analysis of the relative mRNA expression level between transcriptomic data and qPCR data was performed using Student’s t-test with SPSS 26.0 (v26) software, and the differences were considered significant when the p value < 0.05 (*) and extremely significant when the p value < 0.01 (**). 5.
A highly significant correlation ( r = 0.926, p < 0.01) existed among the disease AUDPC readings at three different trials.
At 48 h, the 30 and 60 μM groups had a highly significant lower viability compared with the control ( p < 0.01).
Significant differences were deemed significant, if p -values were below 0.05 ( p ≤ 0.05), and highly significant, if p -values were below 0.01 ( p ≤ 0.01) or 0.001 ( p ≤ 0.001). 5.
When compared with the control, the mRNA expression level of Sp5-HTR1 was significantly upregulated ( p < 0.05) at 0.5 h in the cerebral ganglion, followed by an extremely significant upregulation ( p < 0.01) at 2 h ( Figure 4 B).