Statistical significance was set at p < 0.05, with p < 0.001 indicating a highly significant result and p < 0.0001with highest significant.
Excerpts
These differences were highly significant ( p < 0.0001).
Two-way ANOVA statistical summary demonstrated that the clinical status had a highly significant impact on these levels (F (1, 36) = 26.59, p < 0.0001).
Pairwise comparison between groups at each time revealed that all the test compounds induced a highly significant ( p < 0.0001) reduction in BGL comparable with the standard drug rosiglitazone.
A quantitative analysis on day seven revealed highly significant differences in the number, size and roundness of the spheroids generated by D5 cells compared to control NIH3T3 cells ( p < 0.0001) (Fig. 3 b).
Consistent with the higher protective efficacy seen with antigen combinations compared to individual antigens, Com1/4, Com2/3 and Com1/2/3/4, all induced highly significant IFN-γ ELIspot responses with both immunisation regimens ( p < 0.0001–0.05).
This analysis reproduced the highly significant effect of synchrony (F 1,145.96 = 34.9, p < 0.0001) already found in the 2 × 2 type B model.
Of the 32 datasets with highly significant changes ( P ≤ 0.0001 and |lineal fold change (FC)| ≥ 2) (Fig. 1a ; Supplementary Table S1 ), 26 (81%) presented higher levels of SMARCA4 transcript in tumor samples than in non-tumor samples.
The statistical analysis using ANOVA test with equal sample size across groups ( n = 10) revealed a highly significant difference among the different current levels ( p < 0.0001), indicating that the response was strongly dependent on the magnitude of the applied current.
Although there was no significant residual difference in the CNV size (p = 0.18) or numbers (p = 0.11) between the mGluR+ and mGluR− groups, there was a highly significant difference in the presence of syndromic features between the mGluR+ and mGluR− groups (p < 0.0001).
The differences in Q ′ values between the control and CVD cohorts are highly significant, with two-tailed p -values < 1 × 10 −4 (Fig. 3 and Supplementary Table S3 ).
The effect of adapting speed was highly significant in ANOVA (F(2,8) = 142.57; p < 0.0001; effect size η 2 p = 0.97).
6A ), but 12 days after the induction the difference was highly significant (p = 0.0001, Fig. 6A ).
ANOVA demonstrated highly significant models for both responses (F = 130.35 and 92.02, respectively; p < 0.0001), with extraction solvent volume exerting the most pronounced influence on recovery (F = 315.12), followed by pH (F = 225.51) and disperser volume (F = 151.42) (Table 1 ).
Note that MFI is displayed on a logarithmic scale, and the effect of all three anti-cytokine antibodies was highly significant (p < 0.0001) for IFN-γ.
The association between obese and CRC in overlapping DMRs was highly significant as suggested by Chi square test (p < 0.0001).
The mean percent methylation for the entire region studied was highly significant for the ONB treated groups compared to control ( P < 0.0001) validating our RT-PCR results (Fig. 6c ).
Furthermore, we found a highly significant, negative correlation between PBR values and RBC filling (Person r = − 0.87, p < 0.0001) (Fig. 2 c).
The effect of coating (B-S, M-S, F-S, P-S), test substrate (glass or OTS-SAM coated glass) and treatment conditions (air or water) was highly significant (df = 16, F = 22.7982, p ≤ 0.0001*) as were many of the interactions, including the three-way interaction of coating*surface*treatment ( SI Text, section 3, Table S4 ).
3B ); further statistical analysis revealed a highly significant correlation in antibody titers obtained by PBNA with those by HI or MN (p < 0.0001).
At 3 months the Kruskal–Wallis test indicated a highly significant difference among treatment groups (Kruskal–Wallis H 3 = 23.42; 4 groups, n = 32, p < 0.0001).
The directional biases of the overlapping genes between VSH/NVS and FOR/NUR phenotype were also highly significant (X 2 = 27.52, p < 0.0001 - Table 3 ),with a larger proportion of genes over-expressed in VSH being also over-expressed in nurse antennae, and vice versa .
To statistically assess the overlap between the two gene sets, we performed a Fisher’s Exact test, which demonstrated a highly significant concordance (P < 0.0001, two-sided), indicating that the shared transcriptional response is unlikely to occur by chance (Supplementary Table S1 ).
Highly significant reactivity was found to peptide 17 (P < 0.0001), which yielded a sensitivity of 93%.
In particular, the three EA-HA-L groups exhibited wider and brighter fluorescent bands representing EA, showing extremely significant differences in fluorescent intensity compared to the free EA and EA-L groups (Fig. 2 e, P < 0.0001).