Excerpts

Microbial diversity within samples (alpha diversity) as measured by the Shannon index—which incorporates both microbial richness and evenness—showed highly significant differences across the four study time points ( p = 0.0002) when all dose groups were combined.

In contrast, hypertensive patients exhibited markedly higher concentrations, averaging 3.0 ± 0.7 ng/mL, and this difference was highly significant ( p = 0.0002).

Moreover, linear regression analysis indeed indicated a highly significant (p = 0.0002) positive correlation between O -GlcNAc level and Akt phosphorylation in cervical tissues (Fig. 5 b).

Interestingly, our data revealed that a highly significant increase in myocilin expression (11.8-fold) was observed in TM region of the responder eyes compared to vehicle-treated eyes ( p = 0.0002); and there was a fourfold increase in myocilin expression in GC responder eyes ( p = 0.0004) compared with GC non-responder eyes.

In general, the difference in CYP2W1 expression between normal tissue and primary tumours was highly significant (P ≤ 0.0002).

coli O157:H7 was extremely significant compared to the control ( p = 0.0002), but ratios of Fura-2 with non-target bacteria weren’t found the significant differences compared to the control ( p > 0.05) in the ground beef extract samples.

Moreover, multiple comparison analysis showed highly significant levels of β-III tubulin ( P = 0.0002), Nf-L ( P = 0.0403) and GFAP ( P < 0.015) in the subgroup of CSZ clozapine-treated.

The difference between the cells infected with TTSuV1 and cells transfected with the unrelated DNA was highly significant at p = 0.0002 ( Fig. 2 ).

Water regime under salt stress and QuitoMax application The differences in the water potentials of the varieties in the different treatments were highly significant [F = 108.5; p = 0.00023, F = 112.46; p = 0.000321 for Amalia and Claudia, respectively (Fig. 2 a and b)], and a similar response was found for the osmotic potential (F = 207.32; p = 0.00461, F = 201.31; p = 0.00117 for Amalia and Claudia, respectively).

The ANOVA of the Plackett-Burman design demonstrated that the model was highly significant as was evident from the Fisher’s F -test (51.910) with a very low probability value [ P- value = 0.00024] and the t -Stat of 493.355.

Association mapping revealed highly significant marker trait associations at Bonferroni correction P < 0.00027.

The most significant pathway (P = 0.00001) related to the biology of the innate and adaptive cellular immune response ( Table 2 ), followed by the adaptive response (P = 0.00023) and a number of highly significant and closely related pathways relating to polymorphism in the Fibroblast Growth Factor receptors (FGFR) and their ligands (minimum P = 0.00028).

When analyzing amino acids with reactive side chains, we found in non-transferred peptides a highly significant enrichment of lysine, methionine, and tyrosine and depletion of aspartic acid (P = 0.0003).

MCT1 and MCT4 in relation to PFS and OS Membrane-associated MCT1 exhibited a highly significant impact on PFS (p = 0.0003, log-rank test) and, even more pronounced, on OS (p = 1 × 10 –5 ), see Fig. 2 .

Differences across sites were highly significant for DeepARG results (Kruskal-Wallis, P = 0.0003) with pairwise comparisons showing that SSP had higher relative abundances than CSP (Wilcoxon rank-sum test, BH-corrected; P = 0.0004) and CPT (Wilcoxon rank-sum test, BH-corrected; P = 4.8 × 10−9).

All comparisons between DEA and REF were highly significant (pairwise ANOSIM R ≥ 0.705, p = 0.0003).

The interaction between B-Current and C-pH (BC) was highly significant (F = 38.13, P = 0.0003), indicating that the effect of B-Current on COD removal efficiency is dependent on the C-pH level.

After one week of SFOH intake, a highly significant increase in Fe(2+) and Fe(3+) was observed in the patients' stool supernatant (p = 0.0003 and p = 0.0085, respectively), which then decreased by week 4 (t2, V2, endpoint of the study), but was still significantly higher (p = 0.0028 and p = 0.0424) than at baseline t0 (Fig. 6 ).

near costai G1 (16% rainy, 36% dry) of all mosquitoes collected by season, was highly significant (chi-square = 12.87, p = 0.0003).

The IRC reflection parameters and FSRTF during demineralization showed a trend of decrease (IRC: R = 0.95; p = 0.0003, FSRTF: R = 0.76; p = 0.0286), while the backscattering parameter AIB increased (R = 0.81; p = 0.0148) and FSAB showed an oscillatory behavior with no defined trend (R = 0.23; p = 0.5837), as shown in Fig. 2 .

Being the difference between the two adjusted means (−65.08) highly significant ( p = 0.0003), the most important factor affecting the ASV reduction observed in women with HR-HPV clearance was due to the treatment with the probiotic (Online Resource 16).

zea survival in the bioassay are highly significant (P < 0.0003 and P < 0.0001, respectively) but neither the main effect of soybean nor the cotton * soybean interaction effect is significant (P = 0.2429 and P = 0.0967, respectively).

Therefore, the number of RoH segments in the landlocked population is approximately 1.9–7.7 times higher than those of the anadromous salmon populations, and the differences between them were highly significant (at least, P = 0.0003).

The Pearson correlation test showed a highly significant correlation (r = 0.83; P = 0.0003).

Tapping variability, SD asy A highly significant effect of condition on SD asy was found using a likelihood ratio test (χ 2 (2) = 16.5, p = 0.0003).