Excerpts

Interestingly, a highly significant correlation has been observed between fascin expression and decreased overall survival in African American women with triple-negative breast cancer (TNBC) 18 .

The relative mRNA expression of SRY , SOX9, STAR, CYP11A1 , and LIN28A were analyzed by qPCR, confirming the expression pattern found in the microarray analysis, with significantly different expression of SRY, SOX9 , and CYP11A1 LIN28 between sexes and borderline significant different expression of STAR (Sup.

The three genes received P -values below the Bonferroni threshold (Table 3 ), and the CDC27 was highly significant ( P -value EC = 4.3 × 10 −11 ), surpassing the genome-wide Bonferroni threshold.

Isoprenaline, a beta-adrenergic receptor agonist, at a dose of 3 ug kg −1 did not significantly stimulate cardiac function but a highly significant difference in cardiac output and stroke volume was observed (Fig. 4c,d ).

A total of 32 compounds were quantified, which were grouped in 18 terpenes, 10 alcohols, and 4 aldehydes. In contrast to total free compounds, an increasing trend of total bound terpenes was observed during dehydration for air- and ozone-treated grapes and the maximum contents were found at P30.

A total of 33 volatile compounds were identified and quantified (18 terpenes, 9 alcohols, and 6 aldehydes). Total free terpenes showed a decreasing trend during dehydration for both treatments (air and ozone), although the minimum content was found at P15.

With respect to the different ND electrode configurations, an interesting trend was observed across the different analyses; ND4 had the best ND decoding performance but the worst RSA correlation.

We found that there was a weak trend for the activity time series of nearby cells to be more correlated or anti-correlated than those further away (r 2 = 0.81, Spearman Rank Correlation, or src, −0.80; p = 2.83 × 10 −5 ; Supplementary Fig. 5 ).

Understanding the mechanisms of NP cellular internalization may be significant to develop ways to let NPs enter to the nucleus or other organelles for high curative effect or directly deliver nanomedicine to the lesion site by specific surface modification.

β with respect to rotation angles: in Orientation 2, R2* showed (i) an increasing trend with an increase in bifurcation angle between rotation angles of 0° and 45°, and (ii) a decreasing trend with an increase in bifurcation angle between rotation angles of 45° and 90°.

θ = 90°), R2* showed a decreasing trend as the bifurcation angle (β) was increased for all rotation angles (φ).

As a product of anaerobic decomposition of organic matter, there was a positive trend (Table 4 ) in CH 4 concentrations with the increased DOC concentrations in the rivers of the Tibetan Plateau, indicating that water temperature placed a certain influence on driving pCH 4 increased in anaerobic decomposition in these Tibetan rivers.

Pre-pubertal mice showed a highly significant resistance to mortality from endotoxemia in comparison to post-pubertal mice, despite having equally robust initial responses in cytokine production and leukocyte dynamics.

In this study, irrespectively of the CA cause, most metabolic disturbances showed a trend towards normalization within the first hour after ROSC (Supplementary Fig.

In both models we found a statistical trend for laterality index (Table 3 ).

The follicular CD20+ lymphocyte counts showed an increasing trend from CT group 1 [129.67 (69.08–247.42)/0.1 mm 2 ] to CT group 2 [231.00 (81.83–391.17)/0.1 mm 2 ] to CT group 3 [312.00 (132.96–482.96)/0.1 mm 2 ], but the difference was not statistically significant (p = 0.085) (Table 5 ).

The follicular CD20+ lymphocyte counts showed a trend of gradual elevation from the FVC improved group to the FVC stable group and finally to the FVC worsened group (Table 4 ).

A p value ≤ 0.05 was considered as significant, p > 0.01 highly significant.

The controls for T cells also showed a trend of higher migration towards the positive control, but differences were not significant (Supplementary Fig.

4c left) and a positive trend (albeit not statistically significant) towards an increase in inhibition with higher anti- Pf CSP antibodies was also observed (Fig. 4c right).

The concentrations of most of the PPCPs detected in plasma reflected a decreasing trend that corresponded with the exposure gradient of the caging locations within CPM (CPM1 > CPM2 > CPM3 > JH), except for amitriptyline, citalopram, erythromycin-H 2 O, gemfibrozil, and hydrocortisone.

(2015) reported that TGF-β receptor type 3 was a candidate gene associating with an extremely significant difference in the FCR in chicken 68 .

The −374T > A’s association was only marginally significant under the additive and recessive models.

Although the positive association between the SI and ASI was statistically highly significant, the SI was highly related positively with yield but negatively with fiber length and strength.

The results showed that the expression levels of SP1 and GS1;1 at T1, T2, and T3 in OFA treatment were higher than those in TFA treatment (expect for the expression of SP1 in T2); the differences between the two treatments were significant or highly significant (expect for the expression of GS1;1 in T3).